Cough syrups are composed of menthol and natural extracts, for carminative and antitussive actions. Some Natural extracts are water-insoluble, so alcohol is used as a solvent. Hydroxyl group (R-OH) of alcohol increases miscibility via inter molecular hydrogen bondin with solute particles. This enhances the syrup to be absorbed easily by the body. In addition menthol used as a preservative in pharmaceutical preparations to prevent microbial growth, stabilisers by preventing coagulation of solute particles during storage. |
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